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The Biology of Cancer

The Biology of Cancer
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The Biology of Cancer

 
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M0815340761

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The Biology of Cancer is a textbook for undergraduate and graduate biology students as well as medical students studying the molecular and cellular bases of cancer. The book presents the principles of cancer biology in an organized, cogent, and in-depth manner. The clarity of writing and the lucid full-color art program make the book accessible and engaging. The information unfolds through the presentation of key experiments which give readers a sense of discovery and provides insights into the conceptual foundation underlying modern cancer biology.

The Biology of Cancer synthesizes the findings of three decades of recent cancer research and proposes a conceptual framework from which to teach about these discoveries. It provides the necessary structure, organization, and content for a course on cancer biology for advanced undergraduates and beginning doctoral students. The book is comprehensive and offers many pedagogical features to assist teaching and learning. The book includes many recent and topical references, and is intended to empower the student to move directly into the primary research literature.

The text is up-to-date and provides current information on topics such as tumor stem cells and recently introduced chemotherapeutics. State-of-the-art techniques are discussed throughout. Modern biomedical research is explored, helping readers to hone their analytical abilities and to assimilate and think clearly about complex biological processes. The Biology of Cancer provides insights into many aspects of immunology, developmental biology, and neurobiology.

The exceptional full-color art program contains many images published for the first time. The book is extensively illustrated with schematic drawings, micrographs, computer-generated models and graphs. The pieces were chosen to support and clarify the concepts, as well as to supply additional interest.

Besides its value as a textbook, The Biology of Cancer will be a useful reference for individuals working in biomedical laboratories, and for clinical professionals.

 
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Product Details
Author:Robert A. Weinberg
Paperback:850 pages
Publisher:Garland Science
Publication Date:June 07, 2006
Language:English
ISBN:0815340761
Product Length:10.8 inches
Product Width:8.4 inches
Product Height:1.08 inches
Product Weight:3.9 pounds
Package Length:10.8 inches
Package Width:8.4 inches
Package Height:1.1 inches
Package Weight:3.9 pounds
Average Customer Rating: based on 43 reviews

Customer Reviews
Average Customer Review:5.0 ( 43 customer reviews )
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Most Helpful Customer Reviews

59 of 61 found the following review helpful:


5The State of the Art as it is Known Today.  Aug 12, 2006 By John Matlock "Gunny"
This textbook, aimed at the advanced undergraduate and graduate biology and medical students covers the basic biology of cancer at the molecular andcellular level. Research into cancer in many different directions has been continuing at an accelerated pace since about World War II. In 1975 a major breakthrough was made by H.E. Varmus and J.M. Bishop on San Francisco. The result has been the creation of the new branch of biology covered by this book.

The amount of information discovered in the three decades since then has given us an immense database on the root causes of cancer. The basic discovery that cancer is not one disease but many, some 110 at last count, has led to vast amounts of data.

This book begins to lay out the underlying laws and principles that are beginning to emerge from that data. At the same time, this book is written as a recruiting pamphlet to attract new generations of researchers to move the science forward. While the book points out the discoveries that have been made, it also points out areas where questions remain.

At 850 pages, this is a large book, covering an immense amount of material. In addition there is a CD-ROM with even more material. It has figures, tables, micrographs loaded into Powerpoint presentations that cover each chapter which provides an excellent study aid. There are mini-lectures on various subjects. There are also several movies that will aid in the understanding of some of the processes involved.

A poster 'The Pathways of Human Cancer' summarizes many of the signaling pathways implicated in tumor development. This poster has been produced by Cell Signaling Technology.

The rate of development in the field means that this book will need a new edition shortly, but for the moment this represents the state of the art as it is known today.

19 of 19 found the following review helpful:


5Comprehensive  Mar 10, 2007 By KHB
As a colorectal cancer survivor, I've undertaken a self-study of my cancer in particular, and the disease in general. Saltz's Colorectal Cancer is the comprehensive text for me, but it is better read with a foundation in the nuts and bolts of the disease. Sompayrac's How Cancer Works is a wonderful text for explaining what the nuts and bolts are, but this book, Biology of Cancer, not only explains these in better detail, it also explains how researchers figured all this out. The illustrations, graphs and photos are worth the price of the book itself--you can see the discoveries unfold in front of your own eyes. You don't have to be a scientist to start reading it, but you will probably have to become something of a scientist and retain what you are absorbing as you progress through the book. This is a textbook that is something of an all-star collection of information from a variety of scientific research textbooks.

18 of 18 found the following review helpful:


5Excellent, Fascinating, Well-Written  Jan 03, 2007 By Matthew Kuenzel
This is one of the best books that I have read on any topic. The science of cancer is fascinating because it involves almost all aspects of cell biology. This book presents the subject in a clear, well-organized manner based on the experimental evidence. The author draws conclusions carefully always including possible alternative explanations so the reader senses the full complexity of the problem. He expresses a welcome skepticism about current cancer treatments and frankly discusses the controversies involved. The author has successfully organized a huge body of information in a way that makes it easy to read and understand.

9 of 9 found the following review helpful:


5A fitting textbook from a probable future Nobel laureate  Jun 04, 2008 By S. Lim
First you must consider whom the author is- Dr. Weinberg is a world renowned cancer researcher who has made fundamental contributions to cancer research, discovering some of the most important oncogenes and tumor suppressor genes (Ras and Rb). He's also a member of the national academy of sciences, etc...

As a student working in a cancer research lab, I found the book to be highly instructive.
Sure, I can just read review articles especially Annual Reviews for a lot of the things in the textbook, but there is no better single source for all things related to cancer in one package.
The figures are very nice as well, and they are simplified for easy viewing (FACS plot will not have jagged lines, for example).
However, the book is not missing in terms of primary data either as it has plenty of data from primary sources to demonstrate many of the points.

For example, there is a 50 page chapter on p53 alone.
You're not likely to find a 50 page review article on p53 anywhere else.
And the text is filled with recent references too, as evidenced by a 2006 ChIP paper's figure, referenced in the p53 chapter.

9 of 9 found the following review helpful:


5Biology of Cancer  Jan 09, 2007 By Dr. Christoph Borner "chris borner"
Superbe book, both for scientists and teachers/professors. Clearly written, easy understandable, nicely illustrated and up-to-date...except the concepts of apoptosis. I would have expected that Rob Weinberg talks more about the role of apoptosis deficiency in cancer promotion and resistance to treatment. The biology of cancer is too much "proliferation-driven" in this book. But this is only a minor criticism. The book is really fantastic and should be bought by all lecturers, teachers, professors who have to teach cancer biology.

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